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KMID : 0357520080310010011
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Journal of Radiological Science and Technology
2008 Volume.31 No. 1 p.11 ~ p.16
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Correlation of Effective Dose and BMI in Radioiodine(131I) Therapy
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Shin Gyoo-Seul
Dong Kyung-Rae
Kim Hyun-Soo
Kim Gun-Jae
Dong Kyung-Rae
Kim Hyun-Soo
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Abstract
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Purpose: The aim of this study was to predict radiation dose at 1 meter with BMI(body mass index) in thyroid cancer patients treated with radio-iodine and provide the efficient guideline in the management of patients.
Methods: 140 patients from thyroidectomy for thyroid cancer were enrolled. All subjects under went 150 mCi radio-iodine therapy and performed whole body scan 1 week later. BMI(weight divided by square of height) was calculated to evaluate the amount of fatty tissue indirectly. The radiation dose at 1 meter was measured initially and on 2nd days. the relation of values with BMI were analyzed statically. As for the method of statistical analysis, using Med calc Version 9,2,2,0 Program.
Results: (1) The initial effective dose was inversely correlated with the BMI. Significance level was 0.0004. (2) We obtained the following formula from the data of initial effective dose and BMI: Y = -30.91X + 350.4()(Y: initial radiation dose, x: Group). (3) After 21.55 hours, than radiation dose was less than those recommended by ICRP or NRC in 53% of the population.
Conclusion: Using BMI, the initial radiation dose and 2nd days dose can be predicted in thyroid cancer patients before radio-iodine therapy. It may be used for predicting the time of discharge and control the isolation room. We were able to predict the radiation exposure after discharge using this calculated value.
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KEYWORD
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BMI, Thyroid cancer, Effective dose
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